The First International Conference on Mathematics and Applied Data Science (ICMADS’25) is held between August 29-31, 2025 at Necmettin Erbakan University, Konya, Türkiye, in a hybrid format where both physical and remote participation are allowed. The aim of this conference is to bring together leading researchers, leading experts, and academics in the field of Mathematics and Data Science in order to explore and exchange ideas at the intersection of mathematics and data science, fostering innovation and collaboration.